Archive for January, 2012

NEW YORK ? Lea Michele is moving from a locker to a much bigger closet. She’s the star of the new Candie’s ad campaign, dubbed “Hanging at Home,” shot at a private mansion in Beverly Hills, Calif. The images show her poolside, in the kitchen, in a bed with satin sheets and in a walk-in closet, wearing a new outfit and pair of shoes in each one.

The 25-year-old star of “Glee” is following in the high-heel footprints of former brand spokeswomen Britney Spears and Fergie, among others. Michele says she particularly liked Spears’ old ads. “I think they’re fun and flirty and show off her body great.”

Michele does a little showing off here, too, with some sexy poses, some silly poses and some glamorous ones.

Anyone who has seen Michele do a turn on the red carpet knows she’s got her moves down for the camera.

She has become a “get” for designers eager to show off their gowns on a hot, young starlet. At the recent Golden Globes, she wore a silver Marchesa gown that was straight from the runway.

Her sentimental favorite gown, though, was probably the one she wore to her first Globes in 2010: a black, strapless Oscar de la Renta with a full skirt.

Other tidbits from Michele in an email interview:

AP: What was your wardrobe like in high school?

Michele: My wardrobe in high school was very simple. Jeans and maybe a sweatshirt and sneakers.

AP: Is there a style trend that you love?

Michele: I love wide-leg, high-waisted pants. If done the right way, they’re very chic.

AP: Is there a trend you wish would go away?

Michele: Feathers in people’s hair!

AP: Do you have a guilty pleasure?

Michele: I LOVE beauty products. Face and body creams are my obsession.

The Candie’s brand is available exclusively at Kohl’s Department Stores.

Source: http://us.rd.yahoo.com/dailynews/rss/fashion/*http%3A//news.yahoo.com/s/ap/20120125/ap_on_en_tv/us_fea_fashion_lea_michele_candie_s

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MONTPELIER, Vt. ? The Vermont company that runs much of the electric distribution system in the state is joining with IBM to build a fiber optic control system designed to make the system more efficient and reliable.

The Vermont Electric Power Company and IBM announced Tuesday an agreement to build what’s called an intelligent fiber optic communications and control network across the state.

The system will span more than 1,000 miles and connect transmission substations to Vermont’s distribution utilities and be part of the smart grid that’s being designed.

The companies say IBM will provide project management and networking services. The system will provide the communications capability to relay information back to the utility about usage, existing or potential outages, and equipment performance.

Source: http://us.rd.yahoo.com/dailynews/rss/enterprise/*http%3A//news.yahoo.com/s/ap/20120124/ap_on_bi_ge/us_smart_grid_communication_vermont

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[ Back to EurekAlert! ] Public release date: 23-Jan-2012
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Contact: Rita Sullivan
news@rupress.org
212-327-8603
Rockefeller University Press

Crippling a protein that allows cancer cells to grow when oxygen is scarce causes tumors to regress, according to a study published online on January 23 in the Journal of Experimental Medicine (http://www.jem.org).

An enzyme called PKM2 (M2 isoform of pyruvate kinase) is ramped up in cancer cells, allowing them to generate energy in the harsh, low-oxygen environment found within tumors. Michael Goldberg and Phillip Sharp at the Massachusetts Institute of Technology now find that inhibiting PKM2 kills cancer cells by starving them of energy but leaves normal cells unscathed. Crippling PKM2 caused established tumors in mice to melt away. If these results hold true in humans, this strategy could prove effective against a wide spectrum of cancers with minimal side effects.

###

About the Journal of Experimental Medicine

The Journal of Experimental Medicine (JEM) is published by The Rockefeller University Press. All editorial decisions on manuscripts submitted are made by active scientists in conjunction with our in-house scientific editors. JEM content is posted to PubMed Central, where it is available to the public for free six months after publication. Authors retain copyright of their published works and third parties may reuse the content for non-commercial purposes under a creative commons license. For more information, please visit http://www.jem.org.

Goldberg, M.S., and P.A. Sharp. 2012. J. Exp. Med. doi:10.1084/jem.20111487




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[ Back to EurekAlert! ] Public release date: 23-Jan-2012
[ | E-mail | Share Share ]

Contact: Rita Sullivan
news@rupress.org
212-327-8603
Rockefeller University Press

Crippling a protein that allows cancer cells to grow when oxygen is scarce causes tumors to regress, according to a study published online on January 23 in the Journal of Experimental Medicine (http://www.jem.org).

An enzyme called PKM2 (M2 isoform of pyruvate kinase) is ramped up in cancer cells, allowing them to generate energy in the harsh, low-oxygen environment found within tumors. Michael Goldberg and Phillip Sharp at the Massachusetts Institute of Technology now find that inhibiting PKM2 kills cancer cells by starving them of energy but leaves normal cells unscathed. Crippling PKM2 caused established tumors in mice to melt away. If these results hold true in humans, this strategy could prove effective against a wide spectrum of cancers with minimal side effects.

###

About the Journal of Experimental Medicine

The Journal of Experimental Medicine (JEM) is published by The Rockefeller University Press. All editorial decisions on manuscripts submitted are made by active scientists in conjunction with our in-house scientific editors. JEM content is posted to PubMed Central, where it is available to the public for free six months after publication. Authors retain copyright of their published works and third parties may reuse the content for non-commercial purposes under a creative commons license. For more information, please visit http://www.jem.org.

Goldberg, M.S., and P.A. Sharp. 2012. J. Exp. Med. doi:10.1084/jem.20111487




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Source: http://www.eurekalert.org/pub_releases/2012-01/rup-sip011812.php

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CAMBRIDGE, Mass. ? Actor Jason Segel can add a Hasty Pudding pot award to his career highlights.

Harvard University’s Hasty Pudding Theatricals on Monday named Segel its Man of Year.

The student group is the nation’s oldest undergraduate drama troupe. It’ll host a parade and roast for Segel on Feb. 3.

Segel got his start in the short-lived but critically acclaimed television series “Freaks and Geeks.”

He later wrote and starred in the 2008 movie “Forgetting Sarah Marshall,” which earned more than $100 million worldwide. And he co-wrote and starred in last year’s “The Muppets.”

He plays Marshall Eriksen on the CBS comedy “How I Met Your Mother.”

Last year, Jay Leno won the Hasty Pudding award, which recognizes outstanding entertainers.

Actress Claire Danes has been named this year’s Woman of the Year.

Source: http://us.rd.yahoo.com/dailynews/rss/movies/*http%3A//news.yahoo.com/s/ap/20120124/ap_en_mo/us_people_hasty_pudding_segel

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COLUMBIA, S.C. ? Former House Speaker Newt Gingrich has taken a giant step toward becoming the Republican alternative to Mitt Romney that tea partyers and social conservatives have been seeking for months.

Gingrich’s come-from-behind victory Saturday in the South Carolina primary snatched away the quick and easy way for the GOP to pick its presidential nominee. Only days ago, it seemed that party activists would settle for Romney, the former Massachusetts governor who stirs few passions but who has the looks, money, experience and discipline to make a solid case against President Barack Obama in November.

Now, the party cannot avoid a wrenching and perhaps lengthy nomination fight. It can cast its lot with the establishment’s cool embodiment of competence, forged in corporate board rooms, or with the anger-venting champion of in-your-face conservatism and grandiose ideas.

It’s soul-searching time for Republicans. It might not be pretty.

Romney still might win the nomination, of course. He carries several advantages into Florida and beyond, and party insiders still consider him the front-runner. And it’s conceivable that former Pennsylvania Sen. Rick Santorum can battle back and take the anti-Romney title from Gingrich. After all, he bested Gingrich in Iowa and New Hampshire.

But Santorum’s third-place finish in South Carolina will doubtlessly prompt some conservative leaders to urge him to step aside and back Gingrich, as Texas Gov. Rick Perry did Thursday.

Even if Santorum revives his campaign in Florida, the fundamental intraparty debate will be the same. Voters associate Gingrich and Santorum with social issues such as abortion, and with unyielding fealty to conservative ideals. That’s in contrast to Romney’s flexibility and past embraces of legalized abortion, gun control and gay rights.

Texas Rep. Ron Paul will stay in the race, but he factors only tangentially in such discussions. His fans are largely a mix of libertarians, isolationists and pacifists, many of whom will abandon the GOP nominee if it’s not the Texas congressman.

Strategically, Romney maintains a big edge in money and organization. He faces a dilemma, however. Gingrich resuscitated his struggling campaign in this state with combative debate performances featuring near-contempt for Obama and the news media. Romney likely would love to choke off that supply by drastically reducing the number of debates.

Ducking Gingrich after losing to him in South Carolina would suggest panic or fear, however, and all four candidates are scheduled to debate Monday in Florida.

Gingrich is benefiting “from the inherent animosity and mistrust GOP primary voters have with mainstream media,” said Republican strategist Terry Holt. “Their first instinct is to rebel, and that’s what they did. The question is whether he can sustain that anger and build it into a legitimate challenge to the front-runner.”

Gingrich tried to stoke that anger with his victory speech Saturday. He referred repeatedly to “elites” in Washington and New York who don’t understand or care about working-class Americans. He decried “the growing anti-religious bigotry of our elites.”

Gingrich made $3.1 million in 2010, but he nonetheless is tapping middle-class resentment in ways reminiscent of Sarah Palin. “I articulate the deepest-held values in the American people,” he said.

Despite their contrasting personalities, Romney and Gingrich don’t differ greatly on policy. Both call for lower taxes, less regulation, ending “Obamacare” and a robust military. They promise to cut spending and increase jobs without offering many details of how they would do so in a divided nation and Congress.

Romney versus Gingrich in some ways mirrors the Democrats’ 2008 choice between Obama and Hillary Rodham Clinton. That match-up turned mostly on questions of personality, style and biography. The Republicans’ choice, however, will plumb deeper veins of emotion and ideology.

Romney appeals to Republicans who want a competent, even-tempered nominee with a track record in business and finance. His backers are willing to overlook his past support of abortion rights and his seeming tone-deafness on money matters ? even if it feeds caricatures of him as a tycoon.

Until Saturday, GOP polls had shown Romney easily ahead on the question of who would be Obama’s toughest challenger. South Carolina exit polls, however, showed Gingrich with an edge among those who said it was most important that their candidate be able to beat Obama.

Romney will try to regain that advantage in Florida, which votes Jan. 31. It’s not clear what strategies will work. In his concession speech Saturday, Romney said Obama has attacked free enterprise and “we cannot defeat that president with a candidate who has joined that very assault on free enterprise.”

He was alluding to Gingrich’s past criticisms of Romney’s record running Bain Capital, a private equity firm. But Gingrich and a friendly super PAC dropped their references to Bain days ago.

Romney hinted at another approach. “Our party can’t be led to victory by someone who also has never run a business and never led a state,” he said. Gingrich’s background didn’t seem to bother South Carolina’s Republicans, however.

What they’ve done is steer the primary contest into more emotional, and possibly dangerous, waters. They rewarded a candidate who gave voice to their resentment of the news media, federal bureaucrats and what they see as undeserving welfare recipients and a socialist-leaning president.

Two South Carolina debate moments crystalized Gingrich’s rise. Both involved an open disdain for journalists, whether feigned or not.

In Myrtle Beach on Monday, the Martin Luther King holiday, Gingrich acidly told Fox News’ Juan Williams that he would teach poor people how to find jobs, and that Obama has put more Americans on food stamps than any other president. Gingrich repeated the food stamp lines in his speech Saturday night.

At Thursday’s debate in North Charleston, Gingrich excoriated CNN’s John King for raising the claim by Gingrich’s second wife that Gingrich once asked for an “open marriage” to accommodate his mistress (and now third wife).

Conservatives inside the hall and out seemed to love the tongue-lashing. The details of Marianne Gingrich’s allegations, which Gingrich denied almost as an afterthought, seemed to matter much less to voters. That’s remarkable in a state whose GOP electorate is nearly two-thirds evangelicals.

Mike McKenna, a Republican strategist, said Gingrich seems to be drawing many people, including tea party activists, who are fairly new to politics. They don’t know or care much about Gingrich’s legacy of leading the 1994 Republican revolution in Congress or his lucrative career as a writer and speaker that sometimes veered from conservative orthodoxies, McKenna said.

Instead, he thinks these voters are reacting emotionally to someone they hope “can take the fight to the president, to the media, to whomever. They are not particularly concerned about what kind of president he will be.”

Therein, of course, is the potential peril of a Gingrich candidacy. Along with his verbal fireworks he carries baggage that might give Democrats more to exploit than do Romney’s policy flip-flops and record at Bain.

Gingrich’s impressive South Carolina victory will force Republicans in Florida and other states to make a hot-or-cool choice.

They can pick the data-driven Harvard MBA grad who smoothed out the Winter Olympics and now runs a by-the-numbers nationwide campaign. Or they can pick the pugnacious firebrand who didn’t manage to get his name on the Virginia primary ballot but who wows an angry electorate that can’t wait to lay into Obama in general election debates.

___

EDITOR’S NOTE ? Charles Babington covers politics for The Associated Press.

Source: http://us.rd.yahoo.com/dailynews/rss/politicsopinion/*http%3A//news.yahoo.com/s/ap/20120122/ap_on_an/us_gop_campaign_analysis

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supreme_courtThe U.S. Supreme Court has unanimously decided today to uphold citizens’ Fourth Amendement rights in the GPS tracking case which would have allowed the U.S. government to track a suspects’ cars without a warrant. The court states that the Fourth Amendement’s protection of “persons, houses, papers and effects, against unreasonable searches and seizures,” extends to vehicles.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/RgaTX4cdM54/

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802.11ac, sometimes referred to as 5G or gigabit Wi-Fi, hasn’t been finalized and Apple seldom if ever speaks ahead of time about the incorporation of new technology into the iPhone, iPad, or Mac lines, but they were aggressive in adopting 802.11n while it was in the draft stages and 802.11ac appears to have even more to recommend it.



Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/pQtY2KQsXgQ/story01.htm

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I generally don?t accessorize my iPhone or iPad too much ? I usually find one option that works, and stick with it for the long haul (or at least until



Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/8kXNn7iWMz0/story01.htm

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Syrian army defectors stand guard in front of closed shops at the mountain resort town of Zabadani, Syria, near the Lebanese border, on Friday Jan. 20, 2012. President Bashar Assad’s forces attacked Zabadani, some 17 miles (27 kilometers) west of the capital, for six days, sparking fierce fighting that involved heavy bombardments and clashes with army defectors. On Wednesday, government tanks and armored vehicles pulled back, leaving the opposition in control of the town. Buoyed by the opposition’s control of a town near the Syrian capital, thousands of people held anti-government protests Friday, chanting for the downfall of the regime. At least eight people were killed by security forces across the country, activists said. (AP Photo)

Syrian army defectors stand guard in front of closed shops at the mountain resort town of Zabadani, Syria, near the Lebanese border, on Friday Jan. 20, 2012. President Bashar Assad’s forces attacked Zabadani, some 17 miles (27 kilometers) west of the capital, for six days, sparking fierce fighting that involved heavy bombardments and clashes with army defectors. On Wednesday, government tanks and armored vehicles pulled back, leaving the opposition in control of the town. Buoyed by the opposition’s control of a town near the Syrian capital, thousands of people held anti-government protests Friday, chanting for the downfall of the regime. At least eight people were killed by security forces across the country, activists said. (AP Photo)

Syrian army defectors gather at the mountain resort town of Zabadani, Syria, near the Lebanese border, on Friday Jan. 20, 2012. President Bashar Assad’s forces attacked Zabadani, some 17 miles (27 kilometers) west of the capital, for six days, sparking fierce fighting that involved heavy bombardments and clashes with army defectors. On Wednesday, government tanks and armored vehicles pulled back, leaving the opposition in control of the town. Buoyed by the opposition’s control of a town near the Syrian capital, thousands of people held anti-government protests Friday, chanting for the downfall of the regime. At least eight people were killed by security forces across the country, activists said. (AP Photo)

A Syrian army defector stand guards in front of closed shops at the mountain resort town of Zabadani, Syria, near the Lebanese border, on Friday Jan. 20, 2012. President Bashar Assad’s forces attacked Zabadani, some 17 miles (27 kilometers) west of the capital, for six days, sparking fierce fighting that involved heavy bombardments and clashes with army defectors. On Wednesday, government tanks and armored vehicles pulled back, leaving the opposition in control of the town. Buoyed by the opposition’s control of a town near the Syrian capital, thousands of people held anti-government protests Friday, chanting for the downfall of the regime. At least eight people were killed by security forces across the country, activists said. (AP Photo)

Anti-Syrian regime protesters hold up placards with the names of opposition detainees during a demonstration at the mountain resort town of Zabadani, Syria, near the Lebanese border, on Friday Jan. 20, 2012. President Bashar Assad’s forces attacked Zabadani, some 17 miles (27 kilometers) west of the capital, for six days, sparking fierce fighting that involved heavy bombardments and clashes with army defectors. On Wednesday, government tanks and armored vehicles pulled back, leaving the opposition in control of the town. Buoyed by the opposition’s control of a town near the Syrian capital, thousands of people held anti-government protests Friday, chanting for the downfall of the regime. At least eight people were killed by security forces across the country, activists said. (AP Photo)

Anti-Syrian regime protesters gather at a square as they hold an Arabic banner, center, reading, “hey, the miserable, the tyrant, what else,” during a demonstration at the mountain resort town of Zabadani, Syria, near the Lebanese border, on Friday Jan. 20, 2012. President Bashar Assad’s forces attacked Zabadani, some 17 miles (27 kilometers) west of the capital, for six days, sparking fierce fighting that involved heavy bombardments and clashes with army defectors. On Wednesday, government tanks and armored vehicles pulled back, leaving the opposition in control of the town. Buoyed by the opposition’s control of a town near the Syrian capital, thousands of people held anti-government protests Friday, chanting for the downfall of the regime. At least eight people were killed by security forces across the country, activists said. (AP Photo)

(AP) ? A string of explosions struck a police truck transporting prisoners in a tense area of northwestern Syria on Saturday, killing at least 14 people, the country’s state-run news agency and an opposition group said.

Troops fought intense battles against defectors elsewhere in northern Syria, activists said, leaving “dozens” of people wounded. The 10-month uprising against Syrian President Bashar Assad has turned increasingly militarized and chaotic as more frustrated regime opponents and army defectors arm themselves and fight back against government forces.

SANA news agency blamed the attack on the police truck on “terrorists” and said it occurred on the Idlib-Ariha highway, an area near the Turkish border that has witnessed intense fighting with army defectors recently.

Four bombs that went off in “two phases” hit the truck, and then attackers targeted an ambulance that arrived to assist the wounded, SANA reported.

Six policemen who were accompanying the prisoners were also wounded, some of them in critical condition, it said.

The British-based opposition activist group, the Syrian Observatory for Human Rights, confirmed the incident Saturday and said 15 prisoners were killed.

Rami Abdul-Rahman, director of the group, said the truck was hit by several roadside bombs, but it was not clear who was behind the attack.

There was no immediate claim of responsibility, but members of the so-called Free Syrian Army are known to be active in the area.

A Syria-based activist said the area has several army encampments and is full of roadside bombs planted to target army tanks passing by, adding that the truck carrying prisoners may not have been the intended target.

The activist spoke on condition of anonymity for fear of reprisals.

Abdul-Rahman and other activists in the country’s northern Idlib province also reported heavy clashes between Syrian troops and defectors in the Jabal al-Zawiya region, along the Turkish border.

He said “dozens” of people from both sides were wounded in the fighting, some of them in serious condition.

The Local Coordination Committees activist network said five other people were killed in Syria Saturday, including three in the central city of Homs, one in the eastern city of Deir el-Zour and another in Douma, a suburb of the Syrian capital.

The conflict in Syria has marked the most serious challenge to Assad, who took over from his father in 2000. The U.N. estimates some 5,400 have been killed since March, when the uprising began.

The capital has seen three suicide bombings since late December which the government blamed on terrorist extremists.

The violence comes as the head of an Arab League observers mission was to submit his report to the League’s Cairo headquarters. Foreign ministers for the Arab League will meet Sunday in Cairo to discuss the future of the mission, which expired Thursday.

Arab League officials said the organization is likely to extend its observer mission in Syria and increase its numbers, despite complaints from the Syrian opposition that it has failed to curb the bloodshed in the country.

Members of the Syrian opposition have said Arab observers in Syria have failed to curb the bloodshed and many have called for the dispatch of foreign troops to Syria to create safe zones for dissidents, or even a more wide-ranging military mission similar to the air campaign which helped Libyan rebels bring down dictator Moammar Gadhafi last year.

Burhan Ghalioun, head of the main opposition group, the Syrian National Council, was in the Egyptian capital Saturday for talks with Arab League officials ahead of Sunday’s meeting.

Security officials in Lebanon meanwhile said the Syrian navy arrested three Lebanese fishermen and confiscated their boat Saturday in Lebanese waters off the northern town of Arida.

The two brothers and their nephew were taken after Syria soldiers aboard a naval vessel fired in the direction of the boat, the officials said. They spoke on condition of anonymity in line with regulations.

After the incident, angry residents of Arida blocked the highway linking Lebanon and Syria for hours with burning tires.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2012-01-21-ML-Syria/id-87d65981c02a478981e5708e1fcee11e

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[ Back to EurekAlert! ] Public release date: 19-Jan-2012
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Contact: Kate Taylor
TaylorKa@smh.ca
St. Michael’s Hospital

TORONTO, Ont. Jan. 19, 2012Up to 30 per cent of patients hospitalized after a stroke develop delirium, according to a new study from St. Michael’s Hospital.

Researchers found patients who experience delirium after stroke are five times more likely to die, and are more likely to be discharged to a long-term care facility, nursing home or have a longer stay in hospital.

“Early recognition and prevention of delirium are important for a quick recovery, better quality of life and timely discharge for patients who have suffered a stroke,” said Dr. Gustavo Saposnik, lead author of the paper and director of the Stroke Outcomes Research Centre at the hospital.

Saposnik and colleagues analyzed 10 studies that looked at the four common outcomes in over 2000 patients with delirium inpatient and 12-month death rates, length of hospital stay and care arrangements after discharge.

Unlike dementia a chronic, progressive mental disorientation delirium is an acute, sudden state of confusion is often marked by lack of attention, disorientation, and sometimes hallucination.

Patients can become delirious at any time after a stroke, however when it occurs seven to 10 days later it is commonly related to a complication such as a respiratory or urinary infection, instead of as part of the stroke’s effects.

Recognizing the associated risk factors such as age, severity of stroke, infections, narcotic use, lack of oxygen and cognitive impairment can help clinicians identify initial signs of delirium and use early interventions.

The paper is published in Stroke: Journal of the American Heart Association.

Saposnik said this research aims to encourage early detection and intervention to improve outcomes for patients and families, but further research is needed to understand the most effective interventions.

St. Michael’s Hospital has developed the Delirium Prevention Program (DPP) to reduce the occurrence of delirium especially in elderly patients and to improve patients’ experience.

The DPP is a multi-disciplinary team approach that uses simple strategies in everyday care to help keep patients oriented. Clocks have been installed in every patient’s room along with whiteboards, on which the date is written daily; Lights on the orthopedic unit and overhead paging systems are turned off at night to minimize confusion over time of day; and blinds are opened daily so patients have natural light rhythms.

###

About St. Michael’s Hospital

St. Michael’s Hospital provides compassionate care to all who enter its doors. The Hospital also provides outstanding medical education to future health care professionals in more than 23 academic disciplines. Critical care and trauma, heart disease, neurosurgery, diabetes, cancer care, and care of the homeless are among the Hospital’s recognized areas of expertise. Through the Keenan Research Centre and the Li Ka Shing Knowledge Institute, research at St. Michael’s Hospital is recognized and put into practice around the world. Founded in 1892, the Hospital is fully affiliated with the University of Toronto.

For more information or to speak to Dr. Saposnik please contact:

Kate Taylor
Public Relations Specialist
St. Michael’s Hospital
Phone: 416-864-6060 x6537
TaylorKa@smh.ca



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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


[ Back to EurekAlert! ] Public release date: 19-Jan-2012
[ | E-mail | Share Share ]

Contact: Kate Taylor
TaylorKa@smh.ca
St. Michael’s Hospital

TORONTO, Ont. Jan. 19, 2012Up to 30 per cent of patients hospitalized after a stroke develop delirium, according to a new study from St. Michael’s Hospital.

Researchers found patients who experience delirium after stroke are five times more likely to die, and are more likely to be discharged to a long-term care facility, nursing home or have a longer stay in hospital.

“Early recognition and prevention of delirium are important for a quick recovery, better quality of life and timely discharge for patients who have suffered a stroke,” said Dr. Gustavo Saposnik, lead author of the paper and director of the Stroke Outcomes Research Centre at the hospital.

Saposnik and colleagues analyzed 10 studies that looked at the four common outcomes in over 2000 patients with delirium inpatient and 12-month death rates, length of hospital stay and care arrangements after discharge.

Unlike dementia a chronic, progressive mental disorientation delirium is an acute, sudden state of confusion is often marked by lack of attention, disorientation, and sometimes hallucination.

Patients can become delirious at any time after a stroke, however when it occurs seven to 10 days later it is commonly related to a complication such as a respiratory or urinary infection, instead of as part of the stroke’s effects.

Recognizing the associated risk factors such as age, severity of stroke, infections, narcotic use, lack of oxygen and cognitive impairment can help clinicians identify initial signs of delirium and use early interventions.

The paper is published in Stroke: Journal of the American Heart Association.

Saposnik said this research aims to encourage early detection and intervention to improve outcomes for patients and families, but further research is needed to understand the most effective interventions.

St. Michael’s Hospital has developed the Delirium Prevention Program (DPP) to reduce the occurrence of delirium especially in elderly patients and to improve patients’ experience.

The DPP is a multi-disciplinary team approach that uses simple strategies in everyday care to help keep patients oriented. Clocks have been installed in every patient’s room along with whiteboards, on which the date is written daily; Lights on the orthopedic unit and overhead paging systems are turned off at night to minimize confusion over time of day; and blinds are opened daily so patients have natural light rhythms.

###

About St. Michael’s Hospital

St. Michael’s Hospital provides compassionate care to all who enter its doors. The Hospital also provides outstanding medical education to future health care professionals in more than 23 academic disciplines. Critical care and trauma, heart disease, neurosurgery, diabetes, cancer care, and care of the homeless are among the Hospital’s recognized areas of expertise. Through the Keenan Research Centre and the Li Ka Shing Knowledge Institute, research at St. Michael’s Hospital is recognized and put into practice around the world. Founded in 1892, the Hospital is fully affiliated with the University of Toronto.

For more information or to speak to Dr. Saposnik please contact:

Kate Taylor
Public Relations Specialist
St. Michael’s Hospital
Phone: 416-864-6060 x6537
TaylorKa@smh.ca



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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-01/smh-sfd011912.php

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